Creatine is required for re-synthesis of adenosine triphosphate (ATP) to adenosine diphosphate (ADP). ATP is often called the 'universal energy molecule' because it is used by every cell in our body.
Oxidative stress on cells of the so-called free radicals, together with reduced synthesis of essential energy molecules such as ATP, are indicated as a major cause of faster aging of cells.Production of free radicals increases in stress and physical exertion, while the amount of ATP synthesis decreases with may be concluded that the key factors in maintaining health and delaying the aging process are:
- Reducing damage to the mitochondria of cells from free radicals;
- Reducing the decline in ATP synthesis, which reduces cholesterol levels in the body.
Many of the popular 'anti-aging supplements' have strong antioxidant properties and can fight against free radicals. Other supplements that are focused on that, such as coenzyme Q 10, are necessary for the production of energy compounds such as ATP.
The ability of each cell to function normally depends on the health of the mitochondria and its ability to produce enough ability decreases with age. Heart and nervous system are particularly sensitive to even small changes in ATP levels, which can lead to disturbances in their of all the known additives present, creatine is most effective for increasing levels of ATP, as in this way can reduce the processes of cell damage and slow aging.
Creatine and Aging
One of the biggest problems of people in older age to be healthy and able-bodied is the loss of bone and muscle mass. Bone loss is well known as osteoporosis. But as much attention should be paid and the loss of muscle mass, which is called sarcopenia.
Sarcopenia begins after about 40 years of age and progresses to approximately 75 years. Suffer from it more people leading a sedentary lifestyle, but this is not the only factor for with osteoporosis, there are many reasons: a decline in hormone levels (growth hormone, testosterone, IGF-1), lack of adequate protein and calories in the diet, oxidative stress, inflammation, and loss of motor neurons which determine trophic muscle.
The biggest loss of muscle mass is observed at the expense of FTF - fast-twitch fibers - fast contracting muscle fibers, which determine the strength and speed. These are fibers in which the re-synthesis of ATP depends mainly on creatine phosphate. This leads scientists to conduct research entitled: 'supplementation with creatine enhances isometric strength and body composition after strength training in adults'.
28 adult men and women aged 65 and over were receiving creatine or placebo for 14 weeks during which they have trained with weights. Both groups showed improvement in the power and functionality of muscles. But the group taking creatine showed a much greater increase in muscle mass and strength, and increased content of creatine in muscle cells.
Several other similar studies recorded the same effect, without any side effects which is important to note, as though it is not active athletes and the elderly. One of the studies showed that the positive effects of taking creatine continue even 12 weeks after its discontinuation.